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[Apple](https://www.verizon.com/business/products/mobile/apple/) - [Samsung](https://www.verizon.com/business/products/mobile/samsung/) - [Google](https://www.verizon.com/business/products/mobile/google/) Internet Internet [Internet](https://www.verizon.com) - [Business Internet](#) [Business Internet](https://www.verizon.com/business/resources/articles/s/how-digital-biomarkers-and-connected-devices-are-transforming-clinical-trials/) - [Shop all Business Internet](https://www.verizon.com/business/products/internet/) - [Check internet availability](https://www.verizon.com/foryoursmallbiz/Internet) - [Fios Business Internet](https://www.verizon.com/business/products/internet/fios/) - [5G Business Internet](https://www.verizon.com/business/products/internet/5g/) - [LTE Business Internet](https://www.verizon.com/business/products/internet/lte/) - [Backup and Flexible Use Internet](https://www.verizon.com/business/products/internet/backup-failover/) - [More](#) [More](https://www.verizon.com/business/resources/articles/s/how-digital-biomarkers-and-connected-devices-are-transforming-clinical-trials/) - [Internet Dedicated](https://www.verizon.com/business/products/internet/internet-dedicated/) - [Business Broadband](https://www.verizon.com/business/products/internet/business-broadband/) - [Internet speed test](https://www.verizon.com/business/products/internet/business-speed-test/) - [TechTeam support](https://www.verizon.com/business/products/internet/techteam/) - [Internet usage calculator](https://www.verizon.com/business/products/networks/connectivity/lte-business-internet/lte-internet-usage-calculator/) - [Equipment and devices](#) [Equipment and devices](https://www.verizon.com/business/resources/articles/s/how-digital-biomarkers-and-connected-devices-are-transforming-clinical-trials/) - [Jetpacks and hotspots](https://www.verizon.com/business/shop/products/devices/mobile-hotspots) - [Routers & extenders](https://www.verizon.com/business/products/internet/routers-network-extenders/) - [TV](#) [TV](https://www.verizon.com/business/resources/articles/s/how-digital-biomarkers-and-connected-devices-are-transforming-clinical-trials/) - [Fios TV](https://www.verizon.com/business/products/business-tv/) - [Deals](#) [Deals](https://www.verizon.com/business/resources/articles/s/how-digital-biomarkers-and-connected-devices-are-transforming-clinical-trials/) - [Shop all deals](https://www.verizon.com/business/products/internet/deals/) - [Internet and mobile bundle](https://www.verizon.com/business/products/internet/deals/wireless-internet-phone-bundle/) - [Veteran and military offers](https://www.verizon.com/business/products/deals/discounts/military/) Solutions Solutions [Solutions](https://www.verizon.com) Solutions - [Products](#)[Products](https://www.verizon.com) Products - [Mobile](#)[Mobile](https://www.verizon.com) Mobile - [Shop all mobile](https://www.verizon.com/business/products/mobile/) - [Shop all deals](https://www.verizon.com/business/products/mobile/deals/) - [Mobile plans](https://www.verizon.com/business/products/mobile/plans/) - [Rugged phones](https://www.verizon.com/business/products/mobile/rugged-phones/) - [Bring your own device](https://www.verizon.com/business/products/mobile/plans/bring-your-own-device/) - [Connected laptops](https://www.verizon.com/business/products/mobile/laptops/) - [Apple](https://www.verizon.com/business/products/mobile/apple/) - [Samsung](https://www.verizon.com/business/products/mobile/samsung/) - [Google](https://www.verizon.com/business/products/mobile/google/) - [Internet](#)[Internet](https://www.verizon.com) Internet - [Shop all deals](https://www.verizon.com/business/products/internet/deals/) - [Business Internet](https://www.verizon.com/business/products/internet/) - [Check internet availability](https://www.verizon.com/foryoursmallbiz/Internet) - [Routers & extenders](https://www.verizon.com/business/products/internet/routers-network-extenders/) - [Fios TV](https://www.verizon.com/business/products/internet/business-tv/) - [Tech support](https://www.verizon.com/business/products/internet/service-protection-plan/) - [Internet speed test](https://www.verizon.com/business/products/internet/business-speed-test/) - 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[Voice and collaboration](#)[Voice and collaboration](https://www.verizon.com) Voice and collaboration - [Overview](https://www.verizon.com/business/products/voice-collaboration/) - [One Talk](https://www.verizon.com/business/products/voice-collaboration/one-talk/) - [Webex Cloud Communications](https://www.verizon.com/business/products/voice-collaboration/webex-cloud-communications/) - [Verizon Calling Solutions for Microsoft Teams](https://www.verizon.com/business/products/voice-collaboration/microsoft-teams/) - [VoIP phone services](https://www.verizon.com/business/products/voice-collaboration/voip/) - [Push to Talk Plus](https://www.verizon.com/business/products/voice-collaboration/push-talk-plus/) - [Business & Enterprise Messaging](https://www.verizon.com/business/products/voice-collaboration/business-sms-solutions/) - [Business Assistant](https://www.verizon.com/business/solutions/ai-business-assistant/) - [Plain Old Telephone Service](https://www.verizon.com/business/products/voice-collaboration/plain-old-telephone-service-replacement/) - [Contact centers and CX](#)[Contact centers and CX](https://www.verizon.com) Contact centers and CX - [Overview](https://www.verizon.com/business/products/contact-center-cx/) - [Cloud contact center](https://www.verizon.com/business/products/contact-center-cx/cloud-contact-center/) - [Voice security](https://www.verizon.com/business/products/contact-center-cx/voice-security/) - [Customer engagement](https://www.verizon.com/business/products/contact-center-cx/customer-engagement/) - [Voice services](https://www.verizon.com/business/products/contact-center-cx/voice-services/) - [Voice API solutions](https://www.verizon.com/business/products/contact-center-cx/voice-api/) - [Internet of Things](#)[Internet of Things](https://www.verizon.com) Internet of Things - [Overview](https://www.verizon.com/business/products/internet-of-things/) - [IoT devices](https://www.verizon.com/business/products/internet-of-things/devices/) - [IoT networks](https://www.verizon.com/business/products/internet-of-things/iot-networks/) - [5G Standalone & RedCap](https://www.verizon.com/business/products/internet-of-things/iot-networks/5g-standalone-redcap/) - [IoT platform (ThingSpace) and services](https://www.verizon.com/business/products/internet-of-things/iot-platform-and-services/) - [IoT applications](https://www.verizon.com/business/products/internet-of-things/iot-applications/) - [IoT Satellite Connectivity](https://www.verizon.com/business/products/internet-of-things/satellite-connectivity/) - [Fleet management](https://www.verizonconnect.com?utm_medium=referral&utm_source=verizon&lead=verizonReferral) - [5G Edge](#)[5G Edge](https://www.verizon.com) 5G Edge - [Overview](https://www.verizon.com/business/products/5g-edge/) - [Accelerated Access facial authentication](https://www.verizon.com/business/products/5g-edge/accelerated-access/) - [Crowd Analytics](https://www.verizon.com/business/products/5g-edge/crowd-analytics/) - [Go to all products](https://www.verizon.com/business/products/) - [Industry](#)[Industry](https://www.verizon.com) Industry - [Construction](#)[Construction](https://www.verizon.com) Construction - [Overview](https://www.verizon.com/business/solutions/industry/construction/) - [Future-ready worksites](https://www.verizon.com/business/solutions/industry/construction/future-ready-worksites/) - [Efficient operations](https://www.verizon.com/business/solutions/industry/construction/efficient-operations/) - [Connected workforces](https://www.verizon.com/business/solutions/industry/construction/connected-workforces/) - [Data security](https://www.verizon.com/business/solutions/industry/construction/security-for-workforces-digital-data/) - [Healthcare](https://www.verizon.com/business/solutions/industry/healthcare/) - [Automotive](#)[Automotive](https://www.verizon.com) Automotive - [Overview](https://www.verizon.com/business/solutions/industry/automotive/) - [Connected vehicles](https://www.verizon.com/business/solutions/industry/automotive/autonomous-connected-vehicles/) - [Unified technology](https://www.verizon.com/business/solutions/industry/automotive/autonomous-vehicle-deployment-solutions/) - 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[Personalized customer experiences](https://www.verizon.com/business/solutions/industry/financial/improving-customer-experience/) - [Real-time innovation](https://www.verizon.com/business/solutions/industry/financial/real-time-innovation/) - [Media & entertainment](#)[Media & entertainment](https://www.verizon.com) Media & entertainment - [Overview](https://www.verizon.com/business/solutions/industry/media-entertainment/) - [Intelligent venues](https://www.verizon.com/business/solutions/industry/media-entertainment/intelligent-venues-and-arenas/) - [Connected athletes](https://www.verizon.com/business/solutions/industry/media-entertainment/connected-athletes/) - [Enhance experiences](https://www.verizon.com/business/solutions/industry/media-entertainment/enhancing-customer-venue-experiences/) - [Data and IP protection](https://www.verizon.com/business/solutions/industry/media-entertainment/protect-ip-and-data/) - [Energy & utilities](#)[Energy & utilities](https://www.verizon.com) Energy & utilities - [Overview](https://www.verizon.com/business/solutions/industry/energy-and-utilities/) - [Connected smart grids](https://www.verizon.com/business/solutions/industry/energy-and-utilities/smart-grids/) - [Efficient operations](https://www.verizon.com/business/solutions/industry/energy-and-utilities/operation-efficiencies/) - [Data security](https://www.verizon.com/business/solutions/industry/energy-and-utilities/safeguarding-data/) - [Enhanced customer experiences](https://www.verizon.com/business/solutions/industry/energy-and-utilities/differentiated-cx/) - [Public Sector](#)[Public Sector](https://www.verizon.com) Public Sector - [Overview](https://www.verizon.com/business/solutions/public-sector/) - [Education](https://www.verizon.com/business/solutions/public-sector/education/) - [Federal Government](https://www.verizon.com/business/solutions/public-sector/federal-government/) - [Public Safety](https://www.verizon.com/business/solutions/public-sector/public-safety/) - [State & Local Government](https://www.verizon.com/business/solutions/public-sector/state-local-government/) - 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[Verizon AI Connect](https://www.verizon.com/business/solutions/ai-connect/) - [Verizon Mobile for Microsoft Teams](https://www.verizon.com/business/products/voice-collaboration/microsoft-teams/unified-mobile/) - [Private 5G Network](https://www.verizon.com/business/products/networks/connectivity/private-5g-network/) - [5G Edge computing](https://www.verizon.com/business/solutions/business-intelligence/edge-computing/) - [Supercharge your IT with 5G](https://www.verizon.com/business/solutions/it-infrastructure/5g/) - [Better infrastructure](https://www.verizon.com/business/solutions/build-a-better-infrastructure/) - [One Talk](https://www.verizon.com/business/products/voice-collaboration/one-talk/) - [Public Sector](#)[Public Sector](https://www.verizon.com) Public Sector - [Overview](https://www.verizon.com/business/solutions/public-sector/) - [DBIR for Public Sector](https://www.verizon.com/business/resources/reports/2024-dbir-public-sector-snapshot.pdf) - [Security](https://www.verizon.com/business/products/security/) - 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One of the innovative ways healthcare professionals, researchers and patients are embracing digital healthcare is by creating opportunities to enhance clinical trial participation and information sharing using digital biomarkers. ### The importance of clinical trial participation Clinical trials test the safety and efficacy of medical treatments, therapies and devices. Yet, despite the importance of this process to modern healthcare, clinical trial participation is low—participation rates in trials have been estimated to be somewhere between [3%](https://www.astrazeneca.com/what-science-can-do/topics/clinical-innovation/learning-from-patients-to-make-research-participation-less-of-a-trial.html) and [8%](https://ascopubs.org/doi/full/10.1200/OP.20.01068) of potential participants—and [often unrepresentative](https://acrpnet.org/2020/08/10/representation-in-clinical-trials-a-review-on-reaching-underrepresented-populations-in-research/). These participation challenges have real-world consequences. Approximately [20% of cancer clinical trials fail](https://ascopubs.org/doi/full/10.1200/OP.20.01068) because of insufficient patient enrollment. Meanwhile, clinical trials without appropriately representative participants can miss the opportunity to [assess potential adverse side effects](https://acrpnet.org/2020/08/10/representation-in-clinical-trials-a-review-on-reaching-underrepresented-populations-in-research/) in relevant subsets of the population, such as racial/ethnic minority groups. Location, travel costs, medical mistrust, strict eligibility criteria and scheduling constraints are among the [barriers to effective participation in clinical trials](https://acrpnet.org/2020/08/10/representation-in-clinical-trials-a-review-on-reaching-underrepresented-populations-in-research/). Remote monitoring of patients using biomarker tracking is one way to help overcome some of these barriers to clinical trial participation. A review by pharmaceutical company AstraZeneca found [70% of trial data could be collected remotely](https://www.astrazeneca.com/what-science-can-do/topics/clinical-innovation/learning-from-patients-to-make-research-participation-less-of-a-trial.html). Remote patient monitoring also has [other benefits](https://telehealth.hhs.gov/providers/preparing-patients-for-telehealth/telehealth-and-remote-patient-monitoring/), according to the U.S. government, including reducing the risk of exposure to infection and illnesses, lower rates of hospitalizations and better management of chronic conditions. ### What are digital biomarkers? Digital biomarkers are data obtained by digital devices that can help produce actionable insights into the biological state of individuals. These digital devices are among the [Internet of Medical Things](https://www.verizon.com/business/resources/articles/s/what-the-internet-of-medical-things-means-for-healthcare/) (IoMT) and applications that, [among other uses](https://www.verizon.com/business/resources/articles/s/preparing-for-the-future-of-medical-care/), help connect patients to their healthcare providers remotely, including for digital clinical trials. The underlying technologies, such as a high-performing network that connects to sensors in the relevant devices, are similar to traditional IoT solutions. Information is collected using devices that people wear, have implanted, and, in some cases, digest. Some of the tools that assist with biomarker tracking include: - Wearables—which monitor activity, sleep, heart rate, walking steps, and workouts - Blood pressure monitor—which calculates a person's heart rate and blood flow - Electrocardiogram (ECG)—which evaluates heart health by measuring electrical activity - Glucometer—which measures blood sugar - Keyboards—which can be assessed to measure [keystroke patterns](https://www.forbes.com/sites/ganeskesari/2022/01/31/the-future-of-medicine-fighting-deadly-diseases-with-smart-devices-and-digital-biomarkers/?sh=505c83b22c41) and indicate a change in a person's mobility or brain function These devices use algorithms to process raw data and turn this data into health-related metrics using technology on smartwatches, other wearables, and smartphones, which can be transferred to a patient's electronic health record.  ### Digital biomarkers in clinical trials Research scientists design clinical trials to test the efficacy and safety of new therapies, manage symptoms of diseases and treatments, and optimally prevent diseases. Researchers need data from a lot of people to make a definitive conclusion about efficacy and safety, and digital biomarker tracking creates opportunities for the collection of more data by: - [Improving the patient experience](https://iotpractitioner.com/the-role-of-internet-of-medical-things-iomt-technology-in-transforming-clinical-research/). The adoption of digital biomarkers may help remove some of the impediments to participating in a trial for patients, such as needing to get time off work/school, travel costs, and unwillingness to risk infection or other diseases (for example, some patients may be unwilling to attend a medical facility due to a perceived higher risk of contracting COVID-19). - [Assisting recruitment](https://www.medtechintelligence.com/column/how-the-internet-of-things-will-revolutionize-medical-research/). Digital biomarker tracking makes it easier for researchers to identify and contact candidates who meet relevant criteria for trial participation. - Improving data capture. Passively gathering biometrics from always-on IoMT devices can help address issues of incomplete data, which can cause up to [30% of participants to be excluded from a clinical trial](https://www.medtechintelligence.com/column/how-the-internet-of-things-will-revolutionize-medical-research/). Providing real-time data also allows research personnel to address any issues promptly by alerting them earlier. - [Enhancing data analysis](https://onlinelibrary.wiley.com/doi/abs/10.1002/9781119769200.ch13). This can improve decision-making, including making product or trial design adjustments prior to pre-market and commercial claims and approvals. By leveraging [4G and 5G's data transfer speeds](http://www.verizon.com/about/news/iomt-5g-transform-healthcare/), [artificial intelligence (AI) and machine learning](https://www.verizon.com/business/resources/whitepapers/artificial-intelligence-in-medicine/), and [cloud storage](https://www.verizon.com/business/resources/articles/s/how-cloud-security-best-practices-keep-hospitals-healthy/), researchers can share information across different healthcare systems and take advantage of big data analytics to develop new algorithms and prediction models and improve the quality of diagnosis and prophylaxis. A [Forbes](https://www.forbes.com/sites/ganeskesari/2022/01/31/the-future-of-medicine-fighting-deadly-diseases-with-smart-devices-and-digital-biomarkers/?sh=505c83b22c41) article highlighted the cost savings to trial organizers as well, citing a huge bill—clinical trials cost up to $8 million per day. Phase III studies for new drugs approved by the FDA cost a median of $41,117 per patient. This cost could be brought down by tracking patient adherence to [medicine](https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7993267/) from their home using "smart dosing" technology. These technologies range from "smart packaging" that sends the information to the healthcare provider to ingestibles that allow patients to track health information through saliva or urine. ### A better clinical trial experience The adoption of using digital biomarkers and biomarker tracking in clinical trials is another example of how the future is developing in connected healthcare. As improvements in wireless capabilities and technologies like edge computing and AI expand, they could work together to improve IoMT by creating more opportunities to track patient data, analyze it and provide faster answers in near real time. Wireless in-building connectivity can help in supporting rapid innovation, real-time care decisions and operational efficiency. Learn more about how Verizon is working with healthcare partners to [streamline virtual care](https://www.verizon.com/business/solutions/industry/healthcare/) by providing more opportunities for telehealth and remote care, creating a more inclusive experience for people everywhere. *The author of this content is a paid contributor for Verizon.* - Related articles - Recently published Related articles ### Let's connect. Choose your country to view contact details. 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