How Digital Biomarkers Are Helping to Transforming Clinical Trials Business
How digital biomarkers and connected devices are transforming clinical trials,Author: Lauren Evoy Davis,Digital healthcare has a role to play in making now more than ever before. One of the innovative ways healthcare professionals, researchers and patients are embracing digital healthcare is by creating opportunities to enhance clinical trial participation and information sharing using digital biomarkers. The importance of clinical trial participation,Clinical trials test the safety and efficacy of medical treatments, therapies and devices. Yet, despite the importance of this process to modern healthcare, clinical trial participation is low—participation rates in trials have been estimated to be somewhere between and of potential participants—and . These participation challenges have real-world consequences. Approximately because of insufficient patient enrollment. Meanwhile, clinical trials without appropriately representative participants can miss the opportunity to in relevant subsets of the population, such as racial/ethnic minority groups. Location, travel costs, medical mistrust, strict eligibility criteria and scheduling constraints are among the . Remote monitoring of patients using biomarker tracking is one way to help overcome some of these barriers to clinical trial participation. A review by pharmaceutical company AstraZeneca found . Remote patient monitoring also has , according to the U.S. government, including reducing the risk of exposure to infection and illnesses, lower rates of hospitalizations and better management of chronic conditions. What are digital biomarkers?,Digital biomarkers are data obtained by digital devices that can help produce actionable insights into the biological state of individuals. These digital devices are among the (IoMT) and applications that, , help connect patients to their healthcare providers remotely, including for digital clinical trials. The underlying technologies, such as a high-performing network that connects to sensors in the relevant devices, are similar to traditional IoT solutions. Information is collected using devices that people wear, have implanted, and, in some cases, digest. Some of the tools that assist with biomarker tracking include:,These devices use algorithms to process raw data and turn this data into health-related metrics using technology on smartwatches, other wearables, and smartphones, which can be transferred to a patient's electronic health record. Digital biomarkers in clinical trials,Research scientists design clinical trials to test the efficacy and safety of new therapies, manage symptoms of diseases and treatments, and optimally prevent diseases. Researchers need data from a lot of people to make a definitive conclusion about efficacy and safety, and digital biomarker tracking creates opportunities for the collection of more data by:,A article highlighted the cost savings to trial organizers as well, citing a huge bill—clinical trials cost up to $8 million per day. Phase III studies for new drugs approved by the FDA cost a median of $41,117 per patient. This cost could be brought down by tracking patient adherence to from their home using smart dosing technology. These technologies range from smart packaging that sends the information to the healthcare provider to ingestibles that allow patients to track health information through saliva or urine. A better clinical trial experience,The adoption of using digital biomarkers and biomarker tracking in clinical trials is another example of how the future is developing in connected healthcare. As improvements in wireless capabilities and technologies like edge computing and AI expand, they could work together to improve IoMT by creating more opportunities to track patient data, analyze it and provide faster answers in near real time. Wireless in-building connectivity can help in supporting rapid innovation, real-time care decisions and operational efficiency. Learn more about how Verizon is working with healthcare partners to by providing more opportunities for telehealth and remote care, creating a more inclusiveChoose your country to view contact details. Manage your account or get tools and information. These cookies are necessary for the website to function and cannot be switched off in our systems. They are usually only set in response to actions made by you which amount to a request for services, such as setting your privacy preferences, logging in or filling in forms. 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